Data
INDIAN CONTEXT   

Out of every 100 babies born in this country annually, 6 to 7 have a birth defect. In Indian context, this would translate to 1.7 million birth defects annually and would account for 9.6 per cent of all newborn deaths.With a large birth cohort of almost 26 million per year, India would account for the largest share of birth defects in the world. This would translate to an estimated 1.7 million babies born with birth effects annually. 

Birth defects account for 9.6% of all new-born deaths and 4% of under five mortality. Development delays affect at least 10% children 

Source1. Child health Screening NRHM.2013
 
 
Note.This information complied from the website mentioned above  
Neonatal thyroid dysfunction-lessons from Indian experience   

Worldwide the prevalence of congenital hypothyroidism approximates to 1:3500-1:4000 live births. The exact incidence of congenital hypothyroidism in India is not known. A screening of 36,000 newborns in Chennai as part of a study conducted by Indian council for medical research has revealed that 1.6 in every thousand births had congenital hypothyroidism that results in stunted growth and low intelligence quotient. Newborn screening conducted in 18,300 neonates in Andhra Pradesh reported a prevalence of 1 in 1,700 live births. In another study from North India, revealed a prevalence of 1 in 3,400.

Source=http://www.thetrp.net/article.asp?issn=0973-0354;year=2013;volume=10;issue=4;spage=7;epage=8;aulast=Sundararaman

Note.This information complied from the website mentioned above  
The expression of genetic disease in India

Nearly 5-15 per cent of newborns are sick due to metabolic diseases.

Indian Scenario

1 in every 1,000 newborns was observed .....

Greatest Burden

Importance of screening in India,

Frequency of Genetic Disorders

Staggering

Burdened by rare diseases

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